Lipid characteristics in metastatic cells

摘要: Interest in lipid characteristics of metastatic cells was aroused by the consideration that various components cell membranes influence a broad spectrum surface biological functions which are involved different steps cascade. Correlation between invasive properties and has been appropriately studied limited number systems isolated vivo vitro procedures. The major findings this study have reported review. Among membrane components, glycolipids phospholipids appeared particularly affected tumor acquired phenotype. In fact, reduction complex gangliosides typical transformed lines even more evident highly variant selected from RSV-transformed murine fibroblasts. gangliosides, mainly GD1a, adhesion sites variant. fibrosarcoma line, T3 cells, to be correlated with content expression Gb3ose, glycolipid characteristic line. Moreover, high level ether-linked lipids found variants melanoma lines, as well human mammary carcinomas. considered review discussed for their possible relevance cells.