Acute Paronychia After High-Dose Methotrexate Therapy

摘要: The dermatologic changes that may occur after cancer chemotherapy include cytotoxic effects, pigment alterations, and various eruptions. 1 determination of the causative agent for a dermatosis due to cytostatic drug is often difficult because increased use combination chemotherapy. We describe herein patient with acute paronychia following chemotherapy, which was probably caused by methotrexate sodium; complication that, our knowledge, has not been described previously. Report Case A 73-year-old man had four-year history atypical eczema initially diagnosed as early mycosis fungoides, but disappeared treatment 20 mg/day oral prednisone. Enlargement lymph nodes neck axillae present six months. node biopsy specimen disclosed microscopic malignant lymphoma. then referred hematology department, where he received three