The rapid infusion system: a superior method for the resuscitation of hypovolemic trauma patients

摘要: The rapid infusion system (RIS), which can deliver fluids/blood products rapidly at precise rates and normothermic conditions, was compared with conventional fluid administration (CFA) in a randomized study of 36 hypovolemic trauma patients. Admission stratification criteria the groups were similar relative to age, Glasgow Coma Score (GCS), Injury Severity (ISS) plasma lactate. Despite lack difference blood loss between 24-h survivors two groups, CFA group required greater total fluids (23.6/20.21), red cells (5.5/4.61), fresh frozen (FFP) (2.8/1.91), platelets (523/204 ml), crystalloids (12.9/10.61). Lactate levels lower RIS virtually all times from hours 1 24 (4.3/5.3 mM/l, t-value = 3.3, DF 279, P 0.001). Post-admission hypothermia during first h (35.2/36.4 degrees C, 5.6, 250, mean partial thromboplastin time significantly higher (47.3/35.1 s, 3.1, 0.002). PTT PT related degree lactic acidosis (P 0.0001) 0.001) but not amount FFP given 0.14). hospital costs, days ICU, on ventilator for group, as incidence pneumonia (0/11 vs. 6/17; 0.03). Hypovolemic patients resuscitated needed fewer fluid/blood had less coagulopathy; more resolution hypoperfusion acidosis; better temperature preservation; complications than those methods product administration.