作者: John Morley , Zoltan Kis
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摘要: Xanthine derivatives of formula I wherein R, is C 1-4 alkyl, 3-4 alkenyl or 3-6 cycloalkylmethyl, R 2 alkyl which unsubstituted substituted by one more substituents selected from hydroxy, mercapto, alkoxy and alkylthio, hydrogen, halogen, alkoxy, amino mono- di-(C alkyl)amino 4 5 are each independently amino, alkyl) together represent a methylene dioxy group (-O-CH -O-)-bridging adjacent positions on the phenyl ring, physiologically-hydrolysable -acceptable esters amides thereof; compounds indicated for use as pharmaceuticals in particular treating asthma bronchitis.