Ebola outbreak in Conakry, Guinea: epidemiological, clinical, and outcome features.

摘要: Abstract Objectives The authors studied the epidemiological, clinical, and outcome features of Ebola virus disease in patients hospitalized at treatment center (ETC) Conakry to identify clinical factors associated with death. Materials methods A prospective study was conducted from March 25 August 20, 2014. diagnosis infection made on real-time PCR. Results Ninety patients, a positive test result, were hospitalized. Their mean age 34.12 ± 14.29 years 63% male patients. Most worked informal sector (38%) medical paramedical staff (physicians 12%, nurses 6%, laboratory technicians 1%). lived suburbs (74%) Boffa (11%). main signs physical asthenia (80%) fever (72%). Hemorrhagic observed 26% comparison manifestations showed that hiccups (P = 0.04), respiratory distress hemorrhagic symptoms (P = 0.01) more frequent among who died. Malaria (72%) diabetes (2%) most co-morbidities. crude case fatality rate 44% [95% confidence interval (33–54%)]. average hospital stay 7.96 ± 5.81 days. Conclusion first outbreak characterized by young discrete related lethality. Its control relies strict use preventive measures.