Kynurenic acid antagonises responses to NMDA via an action at the strychnine-insensitive glycine receptor.
作者： Phillip J. Birch , Carol J. Grossman , Ann G. Hayes
DOI: 10.1016/0014-2999(88)90367-6
关键词:
摘要: Kynurenate produces an unsurmountable antagonism of the response to N-methyl-D-aspartate (NMDA) in baby rat hemisected spinal cord. This effect is completely reversible and prevented by co-superfusion with D-serine or glycine presence strychnine. In kynurenate acts as a weak competitive antagonist. The results suggest that one actions antagonise NMDA responses via action at strychnine-insensitive receptor.
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sci-hub.se 参考文章(3)
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