Vapour- and solvent-mediated crystalline transformations in Mo(VI) hydrazone complexes controlled by noncovalent interactions

摘要: The synthesis and structures of the Mo(VI) coordination polymer [MoO2(L)]n (1), mononuclear complexes [MoO2(L)(MeOH)] (2α, 2β, 2γ), salts [MoO2(HL)(MeOH)]X, where X = Cl (3), Br (4), NO3 (5), MeOSO3 (6), L 4-methoxysalicylaldehyde isonicotinoylhydrazonato ligand, are described. Polymer 1 can be quantitatively self-assembled from neutral complex upon vapour-mediated desolvation. efficiency solid-state transformation is driven by proximity reaction centres due to O–H⋯N interactions. Additionally, conversion seems sensitive solvent polarity achieved only in presence polar non-coordinating solvents. In case 3–6, an examination crystal shows that two architecturally different supramolecular assemblies obtained. When anion or Br, hydrogen bonded dimers constructed while infinite hydrogen-bonded 1D chains achieved. deprotonation reactions with Et3N, crystals 3 4 5 6 serve as heteronuclear templates, affording polymorphic forms 2α 2γ, respectively. A common feature 2β association molecules into discrete dimers, whereas formed a consequence bonding non-porous shown undergo single-crystal-to-single-crystal when exposed moisture, thus yielding [MoO2(L)(H2O)] (2w-α). potent broad-spectrum activity 2–6 was established against selected Gram-positive Gram-negative bacteria. cytotoxicity compounds evaluated on HepG2 THP-1 cell lines.