Microtubule Assembly: A Review of Progress, Principles, and Perspectives

摘要: Publisher Summary Substantial improvements in electron, light, and fluorescence microscopy, as well the isolation of discrete protein components cytoskeleton, have led way to a much better appreciation structural organization cytoplasm. Indeed, lacelike network thin filaments, intermediate microtubules nonmuscle cells is familiar today organelles identified after advent biological electron microscopy. A major means for characterizing comprehending emerging principles cytoskeletal action has been isolate define properties various constituents. This chapter considers one such component, microtubule, from perspective theoretical experimental efforts elucidate its assembly disassembly properties. For this purpose, it concentrates on vitro self-assembly derived neural systems.