TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS
作者： Neelima Khairatkar-Joshi , Laxmikant Atmaram Gharat , Vidya Ganapati Kattige , Nagarajan Muthukaman
DOI:
关键词:
摘要: The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These are inhibitors the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme therefore useful in treatment pain and/or inflammation from a variety diseases or conditions, such asthma, osteoarthritis, rheumatoid arthritis, acute chronic neurodegenerative diseases.
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