Updated RA guidelines: Implications for self-care

作者: Brian A. Hemstreet

DOI: 10.1016/J.PTDY.2016.02.009

关键词:

摘要: R arthritis (RA) is a chronic in ammatory condition characterized by polyarticular joint ammation and pain, as well fever, fatigue, myalgias, loss of appetite.1 Extra-articular involvement may result pleuritis, vasculitis, rheumatoid nodules, conjunctivitis. The cause RA unknown, many drug therapies have been approved for treatment. These include synthetic, biologic, or nonbiologic disease-modifying antirheumatic drugs (DMARDs), which target the response through various mechanisms. Medications such NSAIDs corticosteroids are often used adjunctively to provide additional relief pain ammation. Given that considered incurable, optimizing therapy involves use available agents appropriate combination, sequence, timeframe prevent disease progression complications.2

参考文章(6)
I. Hollan, P.H. Dessein, N. Ronda, M.C. Wasko, E. Svenungsson, S. Agewall, J.W. Cohen-Tervaert, K. Maki-Petaja, M. Grundtvig, G.A. Karpouzas, P.L. Meroni, Prevention of cardiovascular disease in rheumatoid arthritis Autoimmunity Reviews. ,vol. 14, pp. 952- 969 ,(2015) , 10.1016/J.AUTREV.2015.06.004
D. H. Solomon, G. W. Reed, J. M. Kremer, J. R. Curtis, M. E. Farkouh, L. R. Harrold, M. C. Hochberg, P. Tsao, J. D. Greenberg, Disease activity in rheumatoid arthritis and the risk of cardiovascular events. Arthritis & Rheumatism. ,vol. 67, pp. 1449- 1455 ,(2015) , 10.1002/ART.39098
Asif Anwar, Imran John Anwar, Patrice Delafontaine, Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs Trends in Cardiovascular Medicine. ,vol. 25, pp. 726- 735 ,(2015) , 10.1016/J.TCM.2015.03.006
Josef S. Smolen, Daniel Aletaha, Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges Nature Reviews Rheumatology. ,vol. 11, pp. 276- 289 ,(2015) , 10.1038/NRRHEUM.2015.8
Anca I. Catrina, Vijay Joshua, Lars Klareskog, Vivianne Malmström, Mechanisms involved in triggering rheumatoid arthritis Immunological Reviews. ,vol. 269, pp. 162- 174 ,(2016) , 10.1111/IMR.12379
Jasvinder A. Singh, Kenneth G. Saag, S. Louis Bridges, Elie A. Akl, Raveendhara R. Bannuru, Matthew C. Sullivan, Elizaveta Vaysbrot, Christine McNaughton, Mikala Osani, Robert H. Shmerling, Jeffrey R. Curtis, Daniel E. Furst, Deborah Parks, Arthur Kavanaugh, James O'Dell, Charles King, Amye Leong, Eric L. Matteson, John T. Schousboe, Barbara Drevlow, Seth Ginsberg, James Grober, E. William St.Clair, Elizabeth Tindall, Amy S. Miller, Timothy McAlindon, 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis: ACR RA Treatment Recommendations Arthritis Care and Research. ,vol. 68, pp. 1- 25 ,(2016) , 10.1002/ACR.22783