Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

作者: Yao-Rong Zheng , Kogularamanan Suntharalingam , Timothy C. Johnstone , Hyunsuk Yoo , Wei Lin

DOI: 10.1021/JA5038269

关键词:

摘要: … We begin with an investigation of the effect of systematically increasing the chain length of … of the extracted material was confirmed using analytical HPLC. As shown in Figure 5, the Pt …

参考文章(55)
Helmut Sigel, Astrid Sigel, Metal complexes in tumor diagnosis and as anticancer agents Marcel Dekker. ,(2004)
Igor V. Tetko, Vsevolod Yu. Tanchuk, Application of associative neural networks for prediction of lipophilicity in ALOGPS 2.1 program. Journal of Chemical Information and Computer Sciences. ,vol. 42, pp. 1136- 1145 ,(2002) , 10.1021/CI025515J
Steven Wyrick, Gail Kaun Till, Stephen G. Chaney, In vitro biotransformations of tetrachloro(d,l-trans)-1,2-diaminocyclohexaneplatinum(IV) (tetraplatin) in rat plasma. Cancer Research. ,vol. 50, pp. 4539- 4545 ,(1990)
Gerald M. Maggiora, Mark A. Johnson, Concepts and applications of molecular similarity Wiley. ,(1990)
Michael A. Jakupec, Markus Galanski, Bernhard K. Keppler, Michael R. Reithofer, Anna K. Bytzek, Seied M. Valiahdi, Christian R. Kowol, Michael Groessl, Christian G. Hartinger, Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes. Journal of Inorganic Biochemistry. ,vol. 105, pp. 46- 51 ,(2011) , 10.1016/J.JINORGBIO.2010.09.006
Bernhard Erdlenbruch, Marit Nier, Wolfgang Kern, Wolfgang Hiddemann, Arnulf Pekrun, Max Lakomek, Pharmacokinetics of cisplatin and relation to nephrotoxicity in paediatric patients European Journal of Clinical Pharmacology. ,vol. 57, pp. 393- 402 ,(2001) , 10.1007/S002280100319
Matthew D. Hall, Howard R. Mellor, Richard Callaghan, Trevor W. Hambley, Basis for design and development of platinum(IV) anticancer complexes. Journal of Medicinal Chemistry. ,vol. 50, pp. 3403- 3411 ,(2007) , 10.1021/JM070280U
Sumitra Mukhopadhyay, Carmen M. Barnés, Ariel Haskel, Sarah M. Short, Katie R. Barnes, Stephen J. Lippard, Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature. Bioconjugate Chemistry. ,vol. 19, pp. 39- 49 ,(2008) , 10.1021/BC070031K
Dong Wang, Stephen J. Lippard, Cellular processing of platinum anticancer drugs. Nature Reviews Drug Discovery. ,vol. 4, pp. 307- 320 ,(2005) , 10.1038/NRD1691
John Christodoulou, John A. Parkinson, Kevin J. Barnham, Alan Tucker, John Woodrow, Peter J. Sadler, Andrei I. Ivanov, Cisplatin Binding Sites on Human Albumin Journal of Biological Chemistry. ,vol. 273, pp. 14721- 14730 ,(1998) , 10.1074/JBC.273.24.14721