Isobutanol Production Using Yeasts With Modified Transporter Expression

作者: Johan Thevelein , Catherine Asleson Dundon , Christopher Smith , Sofie Saerens , Piruz Nahreini

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摘要: The present invention relates to recombinant microorganisms comprising an isobutanol producing metabolic pathway and methods of using said produce isobutanol. In various aspects the invention, may comprise one or more modifications resulting in reduction expression and/or activity endogenous transporter protein. embodiments described herein, be Saccharomyces clade, Crabtree-negative yeast microorganisms, Crabtree-positive post-WGD (whole genome duplication) pre-WGD non-fermenting microorganisms.

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