Process for the preparation of macrocyclic compounds

作者: Wendelin Samstag , Wolfgang Dersch

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摘要: The invention relates to an improved process for the preparation of a macrocyclic compound formula I wherein R 1 , 2 3 A and D have meaning given in claims; by ring closure metathesis corresponding diene III D′ presence benzylidene ruthenium catalyst, phenyl group is substituted nitro group.

参考文章(3)
Montse Llinas-Brunet, Murray D. Bailey, Macrocyclic peptides active against the hepatitis C virus ,(2003)
Chris Hugh Senanayake, Nathan K. Yee, Carl Alan Busacca, Suresh R. Kapadia, Xudong Wei, Azad Hossain, Jianxiu Liu, Nizar Haddad, Fabrice Gallou, Process for preparing macrocyclic compounds ,(2006)