Improved treatment of migraine headache

摘要: This invention comprises a non-vasoactive, supra-vasoactive syndrome ('SVS') minimized dosage form for treatment of migraine in human comprising (i) rapid availability metoclopramide at least about an effective local gastrointestinal amount; (ii) one long acting NSAID such as naproxen sodium therapeutically (iii) wherein said is coordinated form; and, (iv) the absent 5HT agonist vasoactive agents, and preparation thereof. Acid-base stable forms are noted. further methods treatment, introduction oral into small bowel.