Molecular diagnostic and surveillance tools for global malaria control.

摘要: Malaria is the most devastating parasitic infection in world, annually causing over 1 million deaths and extensive morbidity. The global burden of malaria has increased last several decades, as have rates imported into non-endemic regions. Rapid accurate diagnostics are a crucial component control strategies, epidemiological surveillance required to monitor trends prevalence antimalarial drug resistance. Conventional diagnostic tools can be cumbersome slow with limitations both sensitivity specificity. New molecular techniques been developed an attempt overcome these restrictions. These discussed regard their technical advantages disadvantages, emphasis on practicality implementation malaria-endemic