Efficient and selective green extraction of polyphenols from lemon balm

摘要: Abstract Over the past years polyphenolic compounds have attracted much interest, thanks to benefits that they provide when used in formulation of functional foods. They also been broadly investigated for their ability act as free radical scavengers and suitable supplements prevention many cardiovascular neurodegenerative diseases. Lemon balm (Melissa officinalis L.) is well known not only its culinary but curative properties (sedative, spasmolitic, antitumoral, antioxidant). Recent studies shown protocatechuic acid, caffeic rosmarinic acid (RA) are most commonly found phenolic this plant. The present work uses nonconventional methods efficient extraction dried lemon aerial parts. Ultrasound- microwave-assisted protocols were carried out, efficiency selectivity compared. Dry was out on a rewetted vegetal material ball mill presence β-cyclodextrin. Extraction yields, total phenols, RA content all determined. confirmed being main component fractions cases, whereas ethanol best solvent both ultrasound- procedures.