Comparison of Outcomes and Costs Associated With Aspirin ± Clopidogrel After Coronary Artery Bypass Grafting
作者： Ramin Ebrahimi , Sandeep Gupta , Brendan M. Carr , Muath Bishawi , Faisal G. Bakaeen
DOI: 10.1016/J.AMJCARD.2017.12.010
关键词:
摘要: Optimal antiplatelet therapy after coronary artery bypass graft (CABG) surgery remains controversial. This study evaluated the role of dual using aspirin and clopidogrel (DAPT) versus only (ASA) on post-CABG clinical outcomes costs. In Department Veterans Affairs Randomized On/Off Bypass (ROOBY) trial, use CABG was prospectively collected beginning in year 2 this to include 1,525 2,203 original ROOBY patients who received CABG. Discretionarily, surgeons administered either DAPT or ASA treatments. The trial's primary 30-day composite (mortality perioperative morbidity), 1-year (all-cause death, repeat revascularization, nonfatal myocardial infarction), costs were compared for these strategies. Of subjects, 511 1,014 ASA. with had lower rates preoperative left ventricular ejection fraction ≥45% (78.8% vs 85.7%, p
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