Frequency and Phase Synchronization in Distributed (Implantable-Transcutaneous) Neural Interfaces

摘要: Synchronized oscillations are a ubiquitous feature of neuronal circuits and can modulate online information transfer plasticity between brain areas. The disruption these oscillatory processes is associated with the symptoms several disorders. While conventional therapeutic high-frequency deep stimulation perturb oscillations, manipulating timing activity areas more precisely could provide efficient effective method modulating activities. Here we describe prototype circuit for synchronizing clocks an active implantable external sensing system that be used to achieve this goal. Our specific focus on systems paired-associative stimulation. ability repetitively drive two regions fixed latency has implications neural plasticity. Furthermore, general concept applied many potential applications involving distributed interfaces.