From morphological resection to biological benefits: decision and reflection in the treatment of pancreatic adenocarcinoma

摘要: Pancreatic adenocarcinoma (PAC) is a highly lethal disease for human being. Surgery in the past 100 years, novel drug combination and neoadjuvant therapy haven′t changed prognosis of PAC fundamentally. Traditionally, authors only focused on treatment term morphological changes, while it′s tumor biology that will ultimately determine long-term survival patients. Surgeons should continuously pursue radical resection pancreatic cancer, however, with guidance biology. Omics′ researches, artificial intelligence next generation platform translational study improve our understanding PAC. Key words: Pancreas; Neoplasms; Morphology; Biology