Œdème cérébral : nouvelles pistes thérapeutiques

作者: H. Quintard , C. Ichai

DOI: 10.1016/J.ANNFAR.2014.05.007

关键词:

摘要: Cerebral oedema (CO) after brain injury can occur from different ways. The vasogenic and cytotoxic are usually described but osmotic hydrostatic CO, respectively secondary to plasmatic hypotonia or increase in blood pressure, also be encountered. Addition of these several mechanisms worsen injuries. Consequences major, leading quickly death intracerebral hypertension later neuropsychic sequelae. So therapeutic care control this phenomenon is essential osmotherapy actually the only way. A better understanding physiopathological disorders, particularly energetic ways (lactate), aquaporine function, inflammation lead new hopes. promising experimental results need now confirmed by clinical data.

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