Pulmonary Vein Denervation Enhances Long-Term Benefit After Circumferential Ablation for Paroxysmal Atrial Fibrillation
作者： Carlo Pappone , Vincenzo Santinelli , Francesco Manguso , Gabriele Vicedomini , Filippo Gugliotta
DOI: 10.1161/01.CIR.0000112641.16340.C7
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摘要: Background— There are no data to evaluate the relationship between autonomic nerve function modification and recurrent atrial fibrillation (AF) after circumferential pulmonary vein ablation (CPVA). This study assesses incremental benefit of vagal denervation by radiofrequency in preventing AF a large series patients undergoing CPVA for paroxysmal AF. Methods Results— Data were collected on 297 Abolition all evoked reflexes around ostia was defined as complete (CVD) obtained 34.3% patients. Follow-up ended at 12 months. Heart rate variability attenuation, consistent with withdrawal, detectable up 3 months CPVA, particularly CVD, who less likely have than those without (P=0.0002, log-rank test). Only percentage area left isolation CVD predictors recurrence (P<0...
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