PROLIFERATION IN THE EMBRYONIC BRAIN WITH SPECIAL REFERENCE TO THE OVERGROWTH PHENOMENON AND ITS POSSIBLE RELATIONSHIP TO NEOPLASIA.
作者： B. Källén
DOI: 10.1016/S0079-6123(08)63745-0
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摘要: Publisher Summary This chapter discusses the proliferation in embryonic brain with focus on overgrowth phenomenon and its possible relationship to neoplasia. Studies of proliferative processes during normal development vertebrate are reviewed. The occurrence successive intensifications mitotic activity associated formation patterns is demonstrated. presence a number developing nervous system raises problem whether each pattern general increase activity. These apparently due stimulating effect from substratum. Hyperplastic growth can be experimentally provoked by disturbances interaction between substratum neural tube. Neoplasms, partly resembling medulloblastoma tumors humans, may develop within such hyperplastic brains.
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