Random inbreeding, isonymy, and population isolates in Argentina.
作者： José Dipierri , Alvaro Rodríguez-Larralde , Italo Barrai , Jorge López Camelo , Esperanza Gutiérrez Redomero
DOI: 10.1007/S12687-013-0181-X
关键词:
摘要: Population isolates are an important tool in identifying and mapping genes of Mendelian diseases complex traits. The geographical identification represents a priority from genetic health care standpoint. purpose this study is to analyze the spatial distribution consanguinity by random isonymy (FST) Argentina its relationship with previously identified country. FST was estimated surname 22.6 million electors registered for year 2001 24 provinces, 5 regions, 510 departments Statistically significant clustering determined using SaTScan V5.1 software. exhibited marked regional departamental variation, showing highest values towards North West Argentina. clusters high followed same distribution. Recognized Argentinean mainly localized at north country, inbreeding. Given availability listings surnames high-capacity storage devices different countries, estimating them can provide information on inbreeding all levels administrative subdivisions, be used as demographic variable within country public purposes.
springer.com
sci-hub.se 参考文章(49)
E. E. Castilla, R. Sod, The Surveillance of Birth Defects in South America: II. The Search for Geographic Clusters: Endemics Springer Berlin Heidelberg. pp. 211- 230 ,(1990) , 10.1007/978-3-642-75599-6_7
John H Relethford, Estimation of kinship and genetic distance from surnames. Human Biology. ,vol. 60, pp. 475- 492 ,(1988)
N Yasuda, T Furusho, Random and nonrandom inbreeding revealed from isonymy study. I. Small cities of Japan. American Journal of Human Genetics. ,vol. 23, pp. 303- 316 ,(1971)
C Scapoli, A Rodriguez-Larralde, I Barrai, E Mamolini, Isonymy and isolation by distance in Italy. Human Biology. ,vol. 71, pp. 947- 961 ,(1999)
Jorge S. Lopez-Camelo, Joaquin E. Paz, Eduardo E. Castilla, Maria Atilia Gomez, Frequency of first-cousin marriages from civil marriage certificates in Argentina. Human Biology. ,vol. 63, pp. 203- 210 ,(1991)
G. Velázquez, Las regionalizaciones argentinas: evolución de su capacidad de discriminación del bienestar de la población (1943-1992) Geofocus: Revista Internacional de Ciencia y Tecnología de la Información Geográfica. pp. 18- 43 ,(2008)
Leena Peltonen, Aarno Palotie, Kenneth Lange, Use of population isolates for mapping complex traits Nature Reviews Genetics. ,vol. 1, pp. 182- 190 ,(2000) , 10.1038/35042049
James C Barton, Charles A Rivers, Sandrine Niyongere, Sean B Bohannon, Ronald T Acton, Allele frequencies of hemojuvelin gene (HJV) I222N and G320V missense mutations in white and African American subjects from the general Alabama population BMC Medical Genetics. ,vol. 5, pp. 29- 29 ,(2004) , 10.1186/1471-2350-5-29
A. Rodriguez-Larralde, A. Gonzales-Martin, C. Scapoli, I. Barrai, The names of Spain: a study of the isonymy structure of Spain. American Journal of Physical Anthropology. ,vol. 121, pp. 280- 292 ,(2003) , 10.1002/AJPA.10209
Graciela Bailliet, Eduardo E Castilla, Julian P Adams, Iêda M Orioli, Verónica L Martínez-Marignac, Silvina M Richard, Néstor O Bianchi, None, Correlation between molecular and conventional genealogies in Aicuña: a rural population from Northwestern Argentina. Human Heredity. ,vol. 51, pp. 150- 159 ,(2001) , 10.1159/000053336