Investigation of the magnetic field effect upon interpolymeric complexes formation based on bovine serum albumin and poly(aspartic acid)

摘要: The study presents a novel strategy for obtaining highly ordered interpolymeric complexes based on protein, bovine serum albumin and synthetic polymer, poly(aspartic acid). In this approach, experimental tests were carried out in the presence of magnetic field different intensities, namely 0.11 T 0.3 T produced by permanent magnets. influence force complexation process resulted self-assembled structures studied means FTIR spectroscopy, X-ray diffraction, DLS, SEM microscopy vitro assay. changes spectra acquired after 24 h exposure connected with conformational secondary structure increased interactions between polymers, particularly when higher intensity was used. Due to large anisotropy susceptibility characteristic both proteins polypeptides, generated assemblies consisting globular nanometric dimensions. This assembly using magnets, along remote manipulation capability can provide versatile, contact-free, inexpensive tool create new, complex materials tailorable characteristics.