Molecular biology of the GABAA receptor: the receptor/channel superfamily
作者： Eric A. Barnard , Mark G. Darlison , Peter Seeburg
DOI: 10.1016/0166-2236(87)90130-5
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摘要: Abstract Complementary DNAs encoding the two subunit types of brain GABA A receptor have been cloned, revealing its full protein primary structure 1 . In another laboratory, same point has now reached for one subunits spinal cord glycine 2 It is illuminating to compare these sequences and those nicotinic acetylcholine receptor. All receptors, in which an ion channel directly gated by binding transmitter, are deduced be members a superfamily exhibit some striking common features their architecture.
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