Initial and 6-Month Results of Biodegradable Poly-l-Lactic Acid Coronary Stents in Humans

摘要: Background—Although metallic stents are effective in preventing acute occlusion and reducing late restenosis after coronary angioplasty, many concerns still remain. Compared with stents, poly-l-lactic acid (PLLA) biodegradable can deliver drugs locally. The aim of this study was to evaluate the feasibility, safety, efficacy PLLA stent. Methods Results—Fifteen patients electively underwent Igaki-Tamai stent implantation for artery stenoses. is made a monopolymer, has thickness 0.17 mm, zigzag helical coil pattern. A balloon-expandable covered sheath system used, expanded by itself its original size an adequate temperature. total 25 were successfully implanted 19 lesions 15 patients, angiographic success achieved all procedures. No thrombosis no major cardiac event occurred within 30 days. Coronary angiography intravascular ultrasound ser...