The complement profile in clinical medicine. Inherited and acquired conditions lowering the serum concentrations of complement component and control proteins.

摘要: The serum complement profile of patients with systemic or discoid lupus erythematosus, synovitis, vasculitides, certain recurrent chronic skin rashes, fulminant infections, particularly Neisseria, may reveal homozygous deficiencies components causally related to the illness. nephritis erythematosus (SLE) is often accompanied by a distinctive which indicates classical pathway activation and can be used as an index success treatment. In membranoproliferative glomerulonephritis (MPGN), hypocomplementemia reflect in type I, nephritic factor amplification loop II, activating terminal III. acute poststreptococcal glomerulonephritis, cause not known but usually differs from that MPGN SLE. these acquired hypocomplementemias, supplements renal biopsy providing diagnostic information.