Insulin Action, Insulin Resistance, and Their Link to Histone Acetylation

Dan P Christensen, Mattias Dahllöf, Morten Lundh, Daniel N Rasmussen, Mette D Nielsen, Nils Billestrup, Lars G Grunnet, Thomas Mandrup-Poulsen, None, Histone Deacetylase (HDAC) Inhibition as a Novel Treatment for Diabetes Mellitus Molecular Medicine. ,vol. 17, pp. 378- 390 ,(2011) , 10.2119/MOLMED.2011.00021

Michael E. Walsh, Arunabh Bhattacharya, Kavithalakshmi Sataranatarajan, Rizwan Qaisar, Lauren Sloane, Md M. Rahman, Michael Kinter, Holly Van Remmen, The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging Aging Cell. ,vol. 14, pp. 957- 970 ,(2015) , 10.1111/ACEL.12387

Elisabet Agardh, Annika Lundstig, Alexander Perfilyev, Petr Volkov, Tove Freiburghaus, Eero Lindholm, Tina Rönn, Carl-David Agardh, Charlotte Ling, Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy. BMC Medicine. ,vol. 13, pp. 182- 182 ,(2015) , 10.1186/S12916-015-0421-5

Sabbir Khan, Gopabandhu Jena, None, The role of butyrate, a histone deacetylase inhibitor in diabetes mellitus: experimental evidence for therapeutic intervention Epigenomics. ,vol. 7, pp. 669- 680 ,(2015) , 10.2217/EPI.15.20

David T. Duong, Mary E. Waltner-Law, Rosalie Sears, Linda Sealy, Daryl K. Granner, Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter. Journal of Biological Chemistry. ,vol. 277, pp. 32234- 32242 ,(2002) , 10.1074/JBC.M204873200

D.J.P. Barker, The Developmental Origins of Adult Disease Journal of The American College of Nutrition. ,vol. 23, pp. 588- ,(2004) , 10.1080/07315724.2004.10719428

Jose M. Lizcano, Dario R. Alessi, The insulin signalling pathway Current Biology. ,vol. 12, ,(2002) , 10.1016/S0960-9822(02)00777-7

Eleftheria Zeggini, Laura J Scott, Richa Saxena, Benjamin F Voight, Jonathan L Marchini, Tianle Hu, Paul IW de Bakker, Gonçalo R Abecasis, Peter Almgren, Gitte Andersen, Kristin Ardlie, Kristina Bengtsson Boström, Richard N Bergman, Lori L Bonnycastle, Knut Borch-Johnsen, Noël P Burtt, Hong Chen, Peter S Chines, Mark J Daly, Parimal Deodhar, Chia-Jen Ding, Alex SF Doney, William L Duren, Katherine S Elliott, Michael R Erdos, Timothy M Frayling, Rachel M Freathy, Lauren Gianniny, Harald Grallert, Niels Grarup, Christopher J Groves, Candace Guiducci, Torben Hansen, Christian Herder, Graham A Hitman, Thomas E Hughes, Bo Isomaa, Anne U Jackson, Torben Jørgensen, Augustine Kong, Kari Kubalanza, Finny G Kuruvilla, Johanna Kuusisto, Claudia Langenberg, Hana Lango, Torsten Lauritzen, Yun Li, Cecilia M Lindgren, Valeriya Lyssenko, Amanda F Marvelle, Christa Meisinger, Kristian Midthjell, Karen L Mohlke, Mario A Morken, Andrew D Morris, Narisu Narisu, Peter Nilsson, Katharine R Owen, Colin NA Palmer, Felicity Payne, John RB Perry, Elin Pettersen, Carl Platou, Inga Prokopenko, Lu Qi, Li Qin, Nigel W Rayner, Matthew Rees, Jeffrey J Roix, Anelli Sandbaek, Beverley Shields, Marketa Sjögren, Valgerdur Steinthorsdottir, Heather M Stringham, Amy J Swift, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Nicholas J Timpson, Tiinamaija Tuomi, Jaakko Tuomilehto, Mark Walker, Richard M Watanabe, Michael N Weedon, Cristen J Willer, Wellcome Trust Case Control Consortium, Thomas Illig, Kristian Hveem, Frank B Hu, Markku Laakso, Kari Stefansson, Oluf Pedersen, Nicholas J Wareham, Inês Barroso, Andrew T Hattersley, Francis S Collins, Leif Groop, Mark I McCarthy, Michael Boehnke, David Altshuler, None, Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes Nature Genetics. ,vol. 40, pp. 638- 645 ,(2008) , 10.1038/NG.120

S. Rome, E. Meugnier, V. Lecomte, V. Berbe, J. Besson, C. Cerutti, S. Pesenti, A. Granjon, E. Disse, K. Clement, E. Lefai, M. Laville, H. Vidal, Microarray analysis of genes with impaired insulin regulation in the skeletal muscle of type 2 diabetic patients indicates the involvement of basic helix-loop-helix domain-containing, class B, 2 protein (BHLHB2) Diabetologia. ,vol. 52, pp. 1899- 1912 ,(2009) , 10.1007/S00125-009-1442-4

Vesco Mutskov, Bruce M. Raaka, Gary Felsenfeld, Marvin C. Gershengorn, The human insulin gene displays transcriptionally active epigenetic marks in islet-derived mesenchymal precursor cells in the absence of insulin expression. Stem Cells. ,vol. 25, pp. 3223- 3233 ,(2007) , 10.1634/STEMCELLS.2007-0325