A Review of Small Molecule Inhibitors and Functional Probes of Human Cathepsin L.
作者： Dibyendu Dana , Sanjai K. Pathak
DOI: 10.3390/MOLECULES25030698
关键词:
摘要: … Not surprisingly, the dysregulated function of cathepsin L has … that helped define cathepsin L biology with exquisite precision … small molecule inhibitors and probes of human cathepsin L, …
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sci-hub.se 参考文章(190)
Michael C. Myers, Parag P. Shah, Scott L. Diamond, Donna M. Huryn, Amos B. Smith, Identification and Synthesis of a Unique Thiocarbazate Cathepsin L Inhibitor Bioorganic & Medicinal Chemistry Letters. ,vol. 18, pp. 210- 214 ,(2008) , 10.1016/J.BMCL.2007.10.107
Andreas M. Vogel, T. Gerster, Expression of a zebrafish Cathepsin L gene in anterior mesendoderm and hatching gland. Development Genes and Evolution. ,vol. 206, pp. 477- 479 ,(1997) , 10.1007/S004270050078
Radim Vicik, Holger Helten, Tanja Schirmeister, Bernd Engels, Rational Design of Aziridine-Containing Cysteine Protease Inhibitors with Improved Potency: Studies on Inhibition Mechanism ChemMedChem. ,vol. 1, pp. 1021- 1028 ,(2006) , 10.1002/CMDC.200600081
Melissa R. Gardiner, David F. Daggett, Leonard I. Zon, Andrew C. Perkins, Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching. Developmental Dynamics. ,vol. 234, pp. 992- 996 ,(2005) , 10.1002/DVDY.20571
Philip S. Crosier, Anne Bardsley, Julia A. Horsfield, Anna K. Krassowska, Edward R. Lavallie, Lisa A. Collins-Racie, John H. Postlethwait, Yi-Lin Yan, John M. Mccoy, Kathryn E. Crosier, In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins. Developmental Dynamics. ,vol. 222, pp. 637- 644 ,(2001) , 10.1002/DVDY.1218
Hans-Ulrich Demuth, Christoph Schönlein, Alfred Barth, Potent and selective inactivation of proteinases with N-peptidyl-O-acylhydroxylamines Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. ,vol. 996, pp. 19- 22 ,(1989) , 10.1016/0167-4838(89)90088-5
Yukio Nishimura, Takahiro Kawabata, Koji Furuno, Keitaro Kato, Evidence that aspartic proteinase is involved in the proteolytic processing event of procathepsin L in lysosomes. Archives of Biochemistry and Biophysics. ,vol. 271, pp. 400- 406 ,(1989) , 10.1016/0003-9861(89)90289-0
Mona Mostafa Mohamed, Bonnie F. Sloane, Cysteine cathepsins: multifunctional enzymes in cancer Nature Reviews Cancer. ,vol. 6, pp. 764- 775 ,(2006) , 10.1038/NRC1949
Roy Weinstain, Ehud Segal, Ronit Satchi-Fainaro, Doron Shabat, Real-time monitoring of drug release Chem. Commun.. ,vol. 46, pp. 553- 555 ,(2010) , 10.1039/B919329D
Lianne C Hsing, Elizabeth A Kirk, Timothy S McMillen, Shuo-Hung Hsiao, Mark Caldwell, Barbara Houston, Alexander Y Rudensky, Renee C LeBoeuf, None, Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse. Journal of Autoimmunity. ,vol. 34, pp. 96- 104 ,(2010) , 10.1016/J.JAUT.2009.07.003