S-100 Protein in Soft-Tissue Tumors Derived From Schwann Cells and Melanocytes

摘要: In soft tissues outside the central nervous system, S-100 protein is found normally only in Schwann cells. Using peroxidase-antiperoxidase immunohistochemical method was also tumors derived from cells and melanocytes, including neurofibromas, neurilemomas, granular cell myoblastomas, cutaneous nevi, malignant melanomas. not detected Schwannomas, neuroblastomas, oat carcinomas, medullary carcinomas of thyroid, paragangliomas, or meningiomas. absent neoplasms usually considered to arise neural crest origin. appears be a useful marker for identifying melanocytes.