An Epidemic of Food-Borne Listeriosis in Western Switzerland: Description of 57 Cases Involving Adults

摘要: This article describes 57 cases of listeriosis that occurred in adults western Switzerland during an outbreak associated with the consumption a soft cheese. Twenty-one percent were bacteremia, 40% meningitis, and 39% meningoencephalitis. Overall, 42% patients had underlying disease 54% > 65 years age. Patients bacteremia significantly older than those meningitis or meningoencephalitis (median ages, 75, 69, 55 years, respectively). The epidemic strain, defined by phage typing, was isolated three-quarters listerial observed period did not appear to differ from nonepidemic strains terms virulence. overall mortality 32%. Among patients' characteristics, age type clinical presentation independent predictors death multivariate logistic regression model (pseudo-r2 [coefficient determination], .26; both P values < .05), increased risk (odds ratio, 6.5; 95% confidence interval, 1.1-39.5; .05). Neurological sequelae developed 30% survivors CNS listeriosis.