Chapter 46 – Androgen-independent Prostate Cancer: The Evolving Role of Chemotherapy

摘要: Androgen-independent prostate cancer (AIPC) is currently an incurable disease. Recent trials, however, suggest that AIPC can be responsive to novel chemotherapeutic agents. New approaches, including combination chemotherapy and biological therapy, are providing promise for longer survival improved quality of life. The use in has undergone a revolution the past decade. Once labeled “chemotherapy resistant,” new agents have shown great both palliative response endpoints. While been tested extensively phase II only few III trials conducted using Despite dearth data, gaining momentum multitude employing single-agent regimens. microtubule inhibitors targeted group drugs, based on vitro data. Sometimes, hormone therapies also used along with chemotherapy. This known as therapy. Although studies preliminary, therapy deserves further exploration.