Expression of epidermal growth factor, basic fibroblast growth factor and insulin growth factor-1 and relation to myocyte regeneration of obstructed ureters in rats.
作者： Yen-Hwang Chuang , Wan-Long Chuang , Shu-Pin Huang , Chun-Hsiung Huang
DOI: 10.1080/00365590510007649
关键词:
摘要: Objective To investigate the roles of epidermal growth factor (EGF), basic fibroblast (bFGF) and insulin factor-1 (IGF-1) in myocyte regeneration obstructed ureters. Material methods The expression EGF, bFGF, IGF-1 proliferation cell nuclear antigen (PCNA) was studied immunohistochemically 54 female Sprague–Dawley rats. Results Tissue damage to smooth muscle layer ureters aggravated during period obstruction. bFGF myocytes detected using method concurrent immunohistochemical staining. found from Day 14 after ligation. increased a peak on 21 then declined. PCNA also ligation 21. expressions were significantly correlated with of...
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