Current State of Bioabsorbable Polymer-Coated Drug-Eluting Stents

摘要: Drug-eluting stents (DES) have been shown to significantly reduce clinical and angiographic restenosis compared bare metal (BMS). The polymer coatings on DES elute antiproliferative drugs inhibit intimal proliferation prevent after stent implantation. Permanent polymers which do not degrade in vivo may increase the likelihood of stent-related delayed arterial healing or hypersensitivity. In turn, these limitations contribute an increased risk late events. Intuitively, a degrades completion drug release, leaving inert scaffold place, improve by removing chronic source inflammation, neoatherosclerosis, and/or thrombosis. this way, biodegradable ischemic Additionally, improved implantation could requirement for long-term dual antiplatelet therapy associated bleeding cost. This review will focus bioabsorbable polymer-coated currently being evaluated trials.