Dendritic cell vaccines in neurological oncology

摘要: Dendritic cell-based vaccines are an intensively studied active immunotherapy technology. Aim of this article is to review the results key clinical studies such in treatment neuro-oncological diseases. Their effectiveness was most widely malignant glial tumors, study went from experimental work phase III studies, preliminary which indicate some positive method adults. Currently, emphasis also being placed on identification and immunological correlates patient's response therapy search for new antigens sensitization dendritic cells Studies cell include a number other A separate part devoted intracerebral tumors children, example, medulloblastomas gliomas pons. In addition, potential use metastases considered.