Cloning and characterization of a cDNA sequence encoding the precursor of a chlorotoxin-like peptide from the Chinese scorpion Buthus martensii Karsch☆

作者: Xian-Chun Zeng , Wen-Xin Li , Shun-Yi Zhu , Fang Peng , Zhi-Hui Zhu

DOI: 10.1016/S0041-0101(99)00212-3

关键词:

摘要: A full-length cDNA sequence encoding the precursor of a venom peptide with homology to chlorotoxin (named BmKCT) was isolated from library made glands Chinese Scorpion Buthus martensii Karsch. The encoded BmKCT 59 amino acid residues long including signal 24 and mature toxin 35 four disulfide bridges. is similar (68% identities) that Leiurus quinguestriatus quinquestriatus. first report sequences four-disulfide-bridged short-chain toxins martensuii Karsch so far.

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