Interactions between dietary chicory, gut microbiota and immune responses

摘要: This thesis provides a better understanding of interactions between diet, gut microbiota, and immune responses to specific dietary fiber source, chicory (Cichorium intybus L). was achieved by examining the impact on animal performance, digestibility, development, commensal bacteria community structure in small large intestine, follow-up reactions with components, cytoprotective heat shock protein (HSP) 27 72, vivo vitro. The impacts nutrient utilization, environment morphology were investigated chickens young pigs. One-day-old chicks fed cereal-based diets inclusion 60 or 120 g/kg forage and/or root, each diet derived from two harvests. Growing pigs without 80 160 root. The results showed that maintained good performance accompanied changes morphology. Total tract apparent digestibility non-starch polysaccharides (NSP) uronic acid broilers decreased chicory, but not g/kg. indicates can be used as palatable source for broiler Gut microbiota complexity NSP-induced examined using terminal restriction fragment length polymorphism (T-RFLP). analysis revealed four primary clusters: luminal mucosal ileal colonic microbiota. In ileum, lactic (LAB) dominant responsive inulin-type fructan. colon, belonging clostridial cluster IV XIVa responded pectin, whereas Prevotella related cereal xylan. Mapping HSP27 HSP72 occurrence porcine region- cell type-specific features. Physiological expression correlated LAB, representing an important interplay HSPs microbes. In-depth studies lactobacilli mucosa their effects barrier function HSP protective enhancing tight junction under pathogen challenge.