Outbreak of Human Pneumonic Plague with Dog-to-Human and Possible Human-to-Human Transmission--Colorado, June-July 2014.

摘要: On July 8, 2014, the Colorado Department of Public Health and Environment (CDPHE) laboratory identified Yersinia pestis, bacterium that causes plague, in a blood specimen collected from man (patient A) hospitalized with pneumonia. The organism had been previously misidentified as Pseudomonas luteola by an automated system hospital laboratory. An investigation led Tri-County (TCHD) revealed patient A's dog died recently hemoptysis. Three other persons who contact dog, one whom also A, were ill fever respiratory symptoms, including two radiographic evidence Specimens all three human contacts yielded acute Y. pestis infection. One pneumonia cases might have resulted through human-to-human transmission which would be first such event reported United States since 1924. This outbreak highlights 1) need to consider plague differential diagnosis domestic animals, dogs, areas where is endemic; 2) limitations diagnostic systems for identifying rare bacteria pestis; 3) potential milder illness patients taking antimicrobial agents. Hospital laboratorians should aware identification systems, clinicians suspect clinically compatible symptoms P. isolated.