Adherence to antihypertensive therapy affects Ambulatory Arterial Stiffness Index
作者： Andrea Berni , Elisa Ciani , Ilaria Cecioni , Loredana Poggesi , Rosanna Abbate
DOI: 10.1016/J.EJIM.2010.07.015
关键词:
摘要: Abstract Background A major contributor to poor blood pressure (BP) control is nonadherence therapy, which remains poorly recognized by physicians. The prevention of hypertension-induced changes in arterial wall, namely increased stiffness and peripheral vascular resistance, a reasoned adequate end-point hypertension treatment. Indirect measurement these factors can be derived from the analysis 24-hour Ambulatory BP Monitoring (24 h-ABPM). This pilot study evaluated association between antihypertensive therapy adherence 24 h-ABPM-derived parameters hypertensive patients. Methods We studied 42 patients (70 ± 10 years) chronic therapy. Patients were divided according Morisky Medication Adherence Scale (MMAS) Low-Adher (MMAS Results group (n = 17) showed higher AASIs compared High-Adher (n = 25). two groups similar terms burden at 24 h-ABPM. inversely related MMAS. MMAS resulted predictor for both AASI (O.R. 0.49, 95% CI 0.31–0.76, P Conclusions Low seems associated with standard AASI. In this setting, could represent an additional information 24 h-ABPM patient evaluation.
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