作者: Thomas L. Dao
DOI: 10.1007/978-3-642-65806-8_11
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摘要: The isolation of estrone in 1929 independently by Doisy (1929) the United States and Butenandt Germany made possible classic experiment Lacassagne (1932) which mammary tumors male mice were induced giving injections estrone. This established a causal relationship between estrogenic hormones tumorigenesis. proof that can influence growth cancer was derived from experiments Huggins Clark (1940) on prostate dog.