Significance of Interleukin-6 in Papillary Thyroid Carcinoma
作者： Toral P. Kobawala , Trupti I. Trivedi , Kinjal K. Gajjar , Darshita H. Patel , Girish H. Patel
DOI: 10.1155/2016/6178921
关键词:
摘要: This study sought to reveal the significance of IL-6 in papillary thyroid carcinoma by determining its circulating levels, tumoral protein, and mRNA expressions. As compared healthy individuals, serum was significantly higher patients with benign diseases PTC. Further, level PTC as diseases. ROC curves also confirmed a good discriminatory efficacy between individuals The associated poor overall survival patients. immunoreactivity high disease Significantly expression observed primary tumour tissues than adjacent normal tissues. protein at both tissue correlated aggressiveness Moreover, significant positive correlation tumours Finally conclusion, has an important role cancer progression. Thus targeting signalling can help clinical management
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