Do antidepressants precipitate youth suicide?: a nationwide pharmacoepidemiological study.

摘要: The association between treatment with Selective serotonin reuptake inhibitors (SSRIs) and suicide in children adolescents on the individual ecological level were examined a nationwide Danish pharmacoepidemiological register-linkage study including all persons aged 10–17 years treated antidepressants during period 1995–1999 (n=2,569) randomly selected control population (n=50,000). A tripartite approach was used. In Part 1, changes youth use of examined. 2, we made an assessment characteristics. 3, analysed relative risk (RR) according to antidepressant corrected for psychiatric hospital contact minimize problem confounding by indication. SSRIs among increased substantially period, but rate remained stable (Part 1). Among 42 suicides nationally at death, none within 2 weeks prior 2). There associated (RR=4.47), however, not quite significant (95% CI: 0.95–20.96), when adjusted severity illness 3). Conclusively, able identify completed adolescents.