Treatment outcome of late steroid-resistant nephrotic syndrome: a study by the Midwest Pediatric Nephrology Consortium

作者: Caroline Straatmann , Rose Ayoob , Rasheed Gbadegesin , Keisha Gibson , Michelle N. Rheault

DOI: 10.1007/S00467-013-2483-Y

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摘要: Background Idiopathic nephrotic syndrome (NS) in children is classified as steroid sensitive or steroid resistant. Steroid sensitivity typically portends a low risk of permanent renal failure. However, some initially steroid-sensitive patients later develop steroid resistance. These patients with late steroid resistance (LSR) are often treated with immunosuppressant medications, but the effect of these additional drugs on the long-term prognosis of LSR is still unknown. Methods A retrospective chart review was performed on patients diagnosed with …

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