Dietary B Vitamins and a 10-Year Risk of Dementia in Older Persons.
作者： Sophie Lefèvre-Arbogast , Catherine Féart , Jean-François Dartigues , Catherine Helmer , Luc Letenneur
DOI: 10.3390/NU8120761
关键词:
摘要: B vitamins may lower the risk of dementia, yet epidemiological findings, mostly from countries with folic acid fortification, have remained inconsistent. We evaluated in a large French cohort older persons associations between dietary and long-term incident dementia. included 1321 participants Three-City Study who completed 24 h recall, were free dementia at time diet assessment, followed for an average 7.4 years. In Cox proportional hazards models adjusted multiple potential confounders, including overall quality, higher intake folate was inversely associated (p trend = 0.02), approximately 50% individuals highest compared to lowest quintile (HR 0.47; 95% CI 0.28; 0.81). No association found B6 B12. conclusion, relatively low baseline status (average 278 µg/day), intakes decreased
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