Antimicrobial treatment of bacterial infections in frail elderly patients: the difficult balance between efficacy, safety and tolerability.

摘要: The elderly population is increasing worldwide and shows an prevalence of frailty. Frailty recognized as important factor for inappropriate drug prescribing in patients. Appropriate prescription, either terms choice or dosage, paramount importance among the frail patients, this requiring need a difficult balance between efficacy, safety tolerability. Bacterial infections are quite frequent elderly, use antimicrobials may be associated with severe adverse events population, especially when presence co-medications and/or co-morbidities. aim paper to argue about most recent published evidences on how prevent major whenever should co-prescribed