Nicotine intake in smokers increases following a single dose of haloperidol

摘要: The effects of oral haloperidol on nicotine intake, subjective measures craving and smoking satisfaction were compared with placebo in light-to-moderate smokers from a post-prandial cigarette during the subsequent hour unrestricted smoking. Subjects smoked significantly more, as measured by blood levels, when they had received haloperidol, although there was no difference between an any measures. These findings may be interpreted to reflect compensatory increase order obtain usual reward. Having achieved levels reward, subjects did not experience decrease or craving.