Comparative Activity of Benzoyl Peroxide and Hexachlorophene

摘要: • The bactericidal effects of benzoyl peroxide (5% lotion) and hexachlorophene (3% colloidal suspension) against Propionibacterium acnes were compared in nine healthy college students who had the microbiological skin lipid characteristics typical acne vulgaris, but no active lesions. Each two medications was applied twice daily, to opposite sides face, for four consecutive weeks. Hexachlorophene effective surface aerobes only slightly P . It marginally reduced free fatty acid concentrations lipids follicular porphyrin fluorescence. Conversely, virtually eliminated induced substantially decreased We conclude that exerts its antimicrobial action follicles inhibits acnes, while effectiveness is limited surface. ( Arch Dermatol 1983;119:577-579)