Pigments from Filamentous Ascomycetes for Combination Therapy.

作者: Róbert Hromádka , Zdeněk Kejík , Milan Jakubek , Robert Kaplánek , Viera Šandriková

DOI: 10.2174/0929867325666180330091933

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摘要: Filamentous ascomycetes (Neurospora and Monascus) have been studied for a long time because of their production secondary metabolites such as microbial pigments. The represent an interesting group compounds with high potential medicinal applications. Many recent studies shown efficacy in the treatment serious pathological states oncological diseases, neurodegenerative diseases hyperlipidaemia. Nevertheless, clinical usability is still limited. However, this problem can be solved by use these combinations other therapeutic agents. This strategy suppress side effects improve efficacy. Moreover, co-application significantly enhance conventional therapies that are used. review summarizes discusses general principles approach, introduced supported numerous examples. In addition, prediction future application methodology included.

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