Complications associated with central venous catheters inserted in critically ill neonates.

摘要: Objective: To assess the incidence and spectrum of complications associated with central venous catheter (CVC) placement in critically ill infant. Design: A prospective study all babies hospitalized a neonatal intensive care unit (NICU) from January 1989 to December 1989. Potential risk factors infection were evaluated by case-control comparison. Setting: Conducted at university-affiliated, tertiary community hospital. Patients: Neonates requiring catheter. Controls consisted noninfected babies. Results: Of 263 neonates, only 13 (4.9%) required CVC insertion. Seventeen CVCs placed these neonates for total duration 600 days (median, 32 days/cannula). Fifteen (88%) cannulas had one or more during its life including dislodgement leakage (53%), occlusion thrombosis (47%), infections (29%), minor bleeding (12%). Five (29%) developed 6 episodes bloodstream 3 sporadic cases due Staphylococcus epidermidis cluster fungemia Malassezia furfur lipid emulsion therapy Infants CVC-associated younger gestational age (24 weeks versus weeks, p=.04) weighed less birth (580 g 1285 g, p =.02). The overall rate was episode per 100 use. Conclusions: may be lifesaving neonate, but occur frequently Use must restricted infants whom alternate delivery routes intravenous support are otherwise unavailable.