作者: Marina E. Zambrotta , John D. Houlé
DOI: 10.1016/B978-0-12-405544-5.00029-0
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摘要: While most recognized for its role in cancer, the mammalian target of rapamycin (mTOR) pathway is emerging as an important mediator nervous system regeneration and repair. miRNAs make up a class regulatory molecules that exert post-transcriptional control over protein components mTOR signaling cascade. Using miRNA-mediated therapy to achieve precise activation may be one approach normalizing various disease states. As information about increases, research will center on how mTOR’s mechanisms go awry pathological states such cancer neuro-degeneration. Elucidating these critical understanding therapeutic overall human health disease.